Autoimmune haemolytic anaemia due to chronic hepatitis C virus infection treated with prednisone, pegylated interferon and ribavirin.
نویسندگان
چکیده
Chronic hepatitis C virus (HCV) infection has been associated with various extrahepatic manifestations, including autoimmune cytopenias. Primary autoimmune haemolytic anaemia (AIHA) has been reported as an unusual extrahepatic manifestation. Combination therapy with pegylated interferon (PEG-IFN) and ribavirin (RBV) is the current treatment of choice for chronic HCV infection. However, this therapeutic regimen can exacerbate underlying autoimmune disorders and may result in a significant anaemia. Though extrahepatic manifestations usually necessitate HCV treatment, the patient with AIHA as an extrahepatic manifestation of HCV infection represents a therapeutic dilemma.
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عنوان ژورنال:
- The Netherlands journal of medicine
دوره 67 3 شماره
صفحات -
تاریخ انتشار 2009